TargetMol

Bombolitin V

Product Code:
 
TAR-T30561
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Bombolitin V is a mast cell degranulosic peptide from the venom of the bumblebee Megabombus Pennsylvanicus.
CAS:
95648-98-9
Molecular Weight:
1730.15
Purity:
0.98
SMILES:
[C@@H](CC1=CN=CN1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CC(N)=O)=O)C(C)C)=O)CC(C)C)=O)=O)[C@H](CC)C)=O)CC(C)C)=O)=O)CC(C)C)=O)CC(C)C)=O)=O)CCCCN)=O)C)=O)CC(C)C)=O)CO)=O)C(N[C@@H](CC(C)C)C(N)=O)=O

References

Dohtsu K, Okumura K, Hagiwara K, Palma MS, Nakajima T. Isolation and sequence analysis of peptides from the venom of Protonectarina sylveirae (Hymenoptera-Vespidae). Nat Toxins. 1993;1(5):271-6. PubMed PMID: 7513243. Schievano E, Mammi S, Monticelli L, Ciardella M, Peggion E. Conformational studies of a bombolitin III-derived peptide mimicking the four-helix bundle structural motif of proteins. J Am Chem Soc. 2003 Dec 17;125(50):15314-23. PubMed PMID: 14664575. Argiolas A, Pisano JJ. Bombolitins, a new class of mast cell degranulating peptides from the venom of the bumblebee Megabombus pennsylvanicus. J Biol Chem. 1985 Feb 10;260(3):1437-44. PubMed PMID: 2578459. Ahmad A, Ranjan S, Zhang W, Zou J, Pyykk? I, Kinnunen PK. Novel endosomolytic peptides for enhancing gene delivery in nanoparticles. Biochim Biophys Acta. 2015 Feb;1848(2):544-53. doi: 10.1016/j.bbamem.2014.11.008. Epub 2014 Nov 15. PubMed PMID: 25445677.