TargetMol

Ro 07-1902

Product Code:
 
TAR-T28549
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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Further Information

Bioactivity:
Ro 07-1902 could enhance the effect of specific antineoplastic agents.
CAS:
68160-71-4
Formula:
C9H13N3O4
Molecular Weight:
227.22
Purity:
0.98
SMILES:
OC(CN1C=CN=C1[N+]([O-])=O)CO/C=C/C

References

Twentyman PR, Workman P. Chemosensitization by lipophilic nitroimidazoles. Br J Cancer. 1983 Jul;48(1):17-26. PubMed PMID: 6871076; PubMed Central PMCID: PMC2011422. Lee FY, Workman P. Nitroimidazoles as modifiers of nitrosourea pharmacokinetics. Int J Radiat Oncol Biol Phys. 1984 Sep;10(9):1627-30. PubMed PMID: 6237080. Chaplin DJ, Sheldon PW, Ahmed I, Adams GE. Potentiation of cyclophosphamide cytotoxicity in vivo: a study with misonidazole and fifteen other 1-substituted 2-nitroimidazoles. Int J Radiat Oncol Biol Phys. 1984 Sep;10(9):1647-51. PubMed PMID: 6480452. Lee FY, Workman P. Interaction of nitroimidazole sensitizers with drug metabolizing enzymes--spectral and kinetic studies. Int J Radiat Oncol Biol Phys. 1986 Aug;12(8):1383-7. PubMed PMID: 3759560.