TargetMol

HP 228

Product Code:
 
TAR-T25507
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T25507-500mg500mgEnquire
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Further Information

Bioactivity:
HP 228 is a heptapeptide by inhibits the induction of nitric oxide synthase.
CAS:
109022-88-0
Molecular Weight:
942.08
Purity:
0.98
SMILES:
C([C@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@H](CCCC)N)=O)CCC(N)=O)=O)=O)=O)CCCNC(=N)N)=O)C(NCC(N)=O)=O)C=3C=4C(NC3)=CC=CC4

References

Schi?th HB, Muceniece R, Wikberg JE. Characterization of the binding of MSH-B, HB-228, GHRP-6 and 153N-6 to the human melanocortin receptor subtypes. Neuropeptides. 1997 Dec;31(6):565-71. PubMed PMID: 9574823. Weinger MB, Chaplan SR, Girten BE, Powell FL. The respiratory effects of the cytokine regulating agent HP 228 alone and in combination with morphine in human volunteers. Pharmacol Biochem Behav. 1998 Mar;59(3):759-66. PubMed PMID: 9512083. Abou-Mohamed G, Papapetropoulos A, Ulrich D, Catravas JD, Tuttle RR, Caldwell RW. HP-228, a novel synthetic peptide, inhibits the induction of nitric oxide synthase in vivo but not in vitro. J Pharmacol Exp Ther. 1995 Nov;275(2):584-91. PubMed PMID: 7473142. Girten B, McPherson S, Lee M, Grethe N, McDowell R, McPherson L, Tuttle RR. Effectiveness of a cytokine restraining agent (CRA (TM)) in attenuating disuse deconditioning induced by hindlimb unloading in rats. J Gravit Physiol. 1995;2(1):P121-2. PubMed PMID: 11538892.