TargetMol

Bulgecin C

Product Code:
 
TAR-T25183
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T25183-100mg100mgEnquire
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TAR-T25183-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Bulgecin C is an O-sulfonated glycopeptides that can enhance the antibacterial activity of beta-lactam antibiotics.
CAS:
92953-56-5
Molecular Weight:
444.41
Purity:
0.98
SMILES:
CC(=O)NC1C(O)C(OS(O)(=O)=O)C(CO)OC1OC1CC(NC1CO)C(O)=O

References

Karlsen S, Hough E, Rao ZH, Isaacs NW. Structure of a bulgecin-inhibited g-type lysozyme from the egg white of the Australian black swan. A comparison of the binding of bulgecin to three muramidases. Acta Crystallogr D Biol Crystallogr. 1996 Jan 1;52(Pt 1):105-14. PubMed PMID: 15299731. Karlsen S, Hough E. Structure of a complex between bulgecin, a bacterial metabolite, and lysozyme from the rainbow trout. Acta Crystallogr D Biol Crystallogr. 1996 Jan 1;52(Pt 1):115-23. PubMed PMID: 15299732. Thunnissen AM, Rozeboom HJ, Kalk KH, Dijkstra BW. Structure of the 70-kDa soluble lytic transglycosylase complexed with bulgecin A. Implications for the enzymatic mechanism. Biochemistry. 1995 Oct 3;34(39):12729-37. PubMed PMID: 7548026. Fibriansah G, Gliubich FI, Thunnissen AM. On the mechanism of peptidoglycan binding and cleavage by the endo-specific lytic transglycosylase MltE from Escherichia coli. Biochemistry. 2012 Nov 13;51(45):9164-77. doi: 10.1021/bi300900t. Epub 2012 Oct 30. PubMed PMID: 23075328.