TargetMol

2-Keto Crizotinib

Product Code:
 
TAR-T19510
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T19510-100mg100mgEnquire
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TAR-T19510-500mg500mgEnquire
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Further Information

Bioactivity:
2-Keto Crizotinib is an active lactam metabolite of crizotinib.
CAS:
1415558-82-5
Molecular Weight:
464.32
Purity:
0.98
SMILES:
O([C@H](C)C1=C(Cl)C(F)=CC=C1Cl)C2=CC(C3=CN(N=C3)C4CC(=O)NCC4)=CN=C2N

References

Balis FM, e al. First-dose and steady-state pharmacokinetics of orally administered crizotinib in children with solid tumors: a report on ADVL0912 from the Children's Oncology Group Phase 1/Pilot Consortium. Cancer Chemother Pharmacol. 2017 Jan;79(1):181-187.