TargetMol

Thalidomide-C2-amido-C2-COOH

Product Code:
 
TAR-T18805
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T18805-100mg100mgEnquire
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TAR-T18805-500mg500mgEnquire
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Further Information

Bioactivity:
Thalidomide-C2-amido-C2-COOH is a compound that includes a CRBN ligand for the E3 ubiquitin ligase, as well as a linker. It is utilized in the development of PROTAC CDK2/9 Degrader-1[1].
CAS:
2353496-84-9
Molecular Weight:
416.38
Purity:
0.98
SMILES:
O=C(O)CCC(=O)NCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

References

Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2019 Dec 6;187:111952.