TargetMol

PROTAC ERα Degrader-1

Product Code:
 
TAR-T18636
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T18636-100mg100mgEnquire
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TAR-T18636-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
PROTAC ERα Degrader-1 is a chemical compound obtained from compound P1 in patent WO2017201449A1. It consists of a ubiquitin E3 ligase binding group, a linker, and a protein binding group. This compound serves as a degrader of estrogen receptor-alpha (ERα).
CAS:
T18636
Molecular Weight:
1120.29
Purity:
0.98
SMILES:
OC1=CC=C(/C(C2=CC=C(OCCN(C)C(COCCOCCNC(C3=CC=C(C(N4[C@@H](C)[C@H](NC([C@H](C)NC)=O)C(N(CC5=C(OC)C=CC6=C5C=CC=C6)C7=C4C=C(C#N)C=C7)=O)=O)C=C3)=O)=O)C=C2)=C(C8=CC=CC=C8)\CC)C=C1

References

Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1.