TargetMol

VH032 thiol

Product Code:
 
TAR-T18600
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T18600-100mg100mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
VH032 thiol (VHL ligand 6) is a VHL ligand that interacts with pan-BET inhibitor JQ1 through a linker to create a PROTAC[1] compound.
CAS:
2098836-54-3
Molecular Weight:
490.64
Purity:
0.98
SMILES:
C([C@@H](NC(C)=O)[C@](C)(C)S)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C=3SC=NC3C)=O)C[C@@H](O)C1

References

Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.