TargetMol

Thalidomide-O-amido-PEG3-C2-NH2

Product Code:
 
TAR-T17915
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is an E3 ligase ligand-linker conjugate which is designed using Thalidomide-based cereblon ligand and a 3-unit PEG linker. This compound is synthesized specifically for utilization in PROTAC technology.
CAS:
1957236-20-2
Molecular Weight:
506.51
Purity:
0.98
SMILES:
O=C(NCCOCCOCCOCCN)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

References

Methods to induce targeted protein degradation through bifunctional molecules. WO 2017007612 A1