TargetMol

cIAP1 Ligand-Linker Conjugates 10

Product Code:
 
TAR-T17901
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T17901-100mg100mgEnquire
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TAR-T17901-500mg500mgEnquire
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Further Information

Bioactivity:
cIAP1 Ligand-Linker Conjugates 10 comprise of an IAP ligand and a PROTAC linker, which facilitates the design of SNIPERs. These conjugates incorporate an IAP ligand that interacts with the E3 ubiquitin ligase, and a PROTAC linker. SNIPERs can be developed using cIAP1 Ligand-Linker Conjugates 10.
CAS:
T17901
Molecular Weight:
893.07
Purity:
0.98
SMILES:
CC(C)C[C@H](NC([C@H]([C@@H](CC1=CC=CC=C1)NC(OCC2C3=C(C=CC=C3)C4=C2C=CC=C4)=O)O)=O)C(NCCOCCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O

References

Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.