TargetMol

DBCO-PEG4-VA-PBD

Product Code:
 
TAR-T17801
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
DBCO-PEG4-VA-PBD is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
CAS:
T17801
Molecular Weight:
1430.6
Purity:
0.98
SMILES:
[H][C@]12N(C(C3=CC(OC)=C(OCCCOC4=C(C=C5C(N=C[C@@]6([H])N(C=C(C7=CC=C(OC)C=C7)C6)C5=O)=C4)OC)C=C3N=C2)=O)C=C(C8=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCC(N9C%10=CC=CC=C%10C#CC%11=CC=CC=C%11C9)=O)=O)=O)=O)=O)C=C8)C1

References

Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.