TargetMol

N3-PEG3-CH2CH2COOH

Product Code:
 
TAR-T16258
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
N3-PEG3-CH2CH2COOH, a PEG-based PROTAC linker, is utilized in the synthesis of BI-3663, BI-4216, and BI-0319. Additionally, Azido-PEG3-acid, a non-cleavable 3-unit PEG ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs).
CAS:
1056024-94-2
Formula:
C9H17N3O5
Molecular Weight:
247.2484
Purity:
0.98
SMILES:
OC(=O)CCOCCOCCOCCN=[N+]=[N-]

References

Popow J, et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62(5):2508-2520.