TargetMol

Bis-Tos-(2-hydroxyethyl disulfide)

Product Code:
 
TAR-T14663
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
CAS:
69981-39-1
Formula:
C18H22O6S4
Molecular Weight:
462.62
Purity:
0.98
SMILES:
O=S(=O)(OCCSSCCOS(=O)(=O)C1=CC=C(C=C1)C)C2=CC=C(C=C2)C

References

Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.