TargetMol

Biotin-PEG3-Mal

Product Code:
 
TAR-T14593
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Biotin-PEG3-Mal is a biotinylated polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs). By introducing the biotin moiety, it enables specific recognition and binding to target proteins. Additionally, the PEG spacer contributes to improved solubility and flexibility of the linker. This compound offers a valuable tool for constructing PROTACs, which hold great potential in targeted protein degradation strategies[1].
CAS:
1431618-70-0
Formula:
C25H39N5O8S
Molecular Weight:
569.67
Purity:
0.98
SMILES:
C(CCCC(NCCOCCOCCOCCNC(CCN1C(=O)C=CC1=O)=O)=O)[C@H]2[C@@]3([C@](CS2)(NC(=O)N3)[H])[H]

References

Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.