TargetMol

Amino-PEG10-amine

Product Code:
 
TAR-T14223
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T14223-100mg100mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T14223-500mg500mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Amino-PEG10-amine is a PEG-based PROTAC linker employed for the conjugation of two mono diethylstilbestrol (DES)-based ligands. This compound offers an alternative approach to the synthesis of highly selective and active ER antagonists, which are crucial for the advancement of endocrine therapy in breast cancer treatment[1].
CAS:
928292-69-7
Formula:
C22H48N2O10
Molecular Weight:
500.62
Purity:
0.98
SMILES:
O(CCOCCOCCOCCOCCOCCN)CCOCCOCCOCCOCCN

References

Shan M, et al. Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor. ACS Chem Biol. 2013 Apr 19;8(4):707-15.