TargetMol

Uridine 5'-diphosphate sodium salt

Product Code:
 
TAR-T13264
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Uridine 5'-diphosphate sodium salt is a selective native agonist of the P2Y6 receptor (EC50: 300 nM; pEC50: 6.52), and also is a potent antagonist of P2Y14 (pEC50: 7.28).
CAS:
21931-53-3
Formula:
C9H11N2Na3O12P2
Molecular Weight:
470.106
Purity:
0.98
SMILES:
[Na+].[Na+].[Na+].OC1C(O)C(OC1COP([O-])(=O)OP([O-])([O-])=O)n1ccc(=O)[nH]c1=O

References

Jacobson KA, et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal. 2009 Mar;5(1):75-89. Kim B, et al. Uridine 5'-diphosphate induces chemokine expression in microglia and astrocytes through activation of the P2Y6 receptor. J Immunol. 2011 Mar 15;186(6):3701-9.