TargetMol

Fradafiban

Product Code:
 
TAR-T11322
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.
CAS:
148396-36-5
Formula:
C20H21N3O4
Molecular Weight:
367.4
Purity:
0.98
SMILES:
O(C[C@@H]1C[C@@H](CC(O)=O)C(=O)N1)C2=CC=C(C=C2)C3=CC=C(C(=N)N)C=C3

References

M?ller TH, et al. Profound and sustained inhibition of platelet aggregation by Fradafiban, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, and its orally active prodrug, Lefradafiban, in men. Circulation. 1997 Aug 19;96(4):1130-8.