TargetMol

(±)-α-Bisabolol

Product Code:
 
TAR-T8199
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
(?)-α-Bisabolol isa sesquiterpenol extracted from essential oils of chamomile, candida and other plants. It isa natural antiseptic with soothing, antiirritating, anti-inflammatory, antioxidant and anticancer activities. (?)-α-Bisabolol has anticancer effects on A549 NSCLC cells by inducing cell cycle arrest, mitochondrial death and inhibiting PI3K/Akt signaling (IC50 = 15 uM). (?)-α-Bisabolol can induce apoptosis of glioma cells.
CAS:
515-69-5
Formula:
C15H26O
Molecular Weight:
222.37
Pathway:
Apoptosis|oxidation-reduction
Purity:
0.9944
SMILES:
CC1=CC[C@H]([C@@](CC/C=C(C)\C)(O)C)CC1
Target:
Apoptosis|Antioxidant

References

de Siqueira RJ, et al. In-vitro characterization of the pharmacological effects induced by (-)-?-bisabolol in rat smooth muscle preparations. Can J Physiol Pharmacol. 2012;90(1):23-35. Fernandes MYD, et al. (-)-?-bisabolol prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice. Eur J Pharmacol. 2019;842:270-280.