TargetMol

TP0427736 hydrochloride

Product Code:
 
TAR-T61029
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T61029-50mg50mg£754.00
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Quantity:
TAR-T61029-100mg100mg£1,163.00
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This product comes from: United States.
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Further Information

Bioactivity:
TP0427736 hydrochloride can be used in the androgenic alopecia (AGA) research. TP0427736 hydrochloride inhibits the phosphorylation of Smad2/3 in A549 cells induced by TGF-β1 with an IC50 value of 8.68 nM. TP0427736 hydrochloride is a potent ALK5 kinase inhibitor with an IC50 value of 2.72 nM which is 300-fold more potent than inhibitory effect against ALK3 of 836 nM [1].
CAS:
2459963-17-6
Molecular Weight:
334.84
Purity:
0.98
SMILES:
Cl.N1=CSC=2C=C(C=CC12)C=3NC=NC3C4=NC(=CS4)C