TargetMol

Nrf2-ARE/hMAO-B/QR2 modulator 1

Product Code:
 
TAR-T60395
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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Further Information

Bioactivity:
Nrf2-ARE/hMAO-B/QR2 modulator 1 is a new resveratrol-based multitarget-directed ligands (MTDLs) that showed a well-balanced MTDL profile: cellular activation of the NRF2-ARE pathway (CD = 9.83 uM), selective inhibition of both hMAO-B and QR2 (IC50s = 8.05 and 0.57 uM), and the best ability to promote hippocampal neurogenesis. Nrf2-ARE/hMAO-B/QR2 modulator 1 exerts neuroprotective and antioxidant actions in both acute and chronic Alzheimer models using hippocampal tissues.
Formula:
C14H12N2O3
Molecular Weight:
256.26
Purity:
0.98