TargetMol

PDD00017273

Product Code:
 
TAR-T5700
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
PDD 00017273 is a potent Poly(ADP-ribose) Glycohydrolase (PARG) inhibitor with an IC 50 of 26 nM and a KD of 1.45 nM [1] [2].
CAS:
1945950-21-9
Molecular Weight:
514.62
Purity:
0.98
SMILES:
Cc1cc(Cn2c3ccc(cc3c(=O)n(Cc3cnc(C)s3)c2=O)S(=O)(=O)NC2(C)CC2)n(C)n1

References

Sun Y, Chen J, Pommier Y.Real-time imaging of drug-induced trapping of cellular topoisomerases and poly (ADP-ribose) polymerase 1 at the single-molecule level.Nucleic Acids Research.2023: gkad735.