TargetMol

Verrucarin A

Product Code:
 
TAR-T41240
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T41240-10mg10mg£1,210.00
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Quantity:
TAR-T41240-25mg25mg£2,020.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Verrucarin A (Muconomycin A) is a Type D macrocyclic mycotoxin. Verrucarin A (VA), a protein synthesis inhibitor, derived from the pathogen fungus Myrothecium verrucaria, inhibits growth of leukemia cell lines and activates caspases and apoptosis and inflammatory signaling in macrophages. Verrucarin A effectively increased the phosphorylation of p38 MAPK and diminished the phosphorylation of ERK/Akt. Verrucarin A caused cell cycle deregulation through the induction of p21 and p53 [1] [2].
CAS:
02/09/3148
Molecular Weight:
488.533
Purity:
0.98
SMILES:
C[C@@H]1CCOC(=O)\C=C\C=C/C(=O)O[C@@H]2CC3OC4C=C(C)CC[C@]4(COC(=O)[C@H]1O)C2[C@@]31CO1