TargetMol

Murrangatin

Product Code:
 
TAR-TN4592
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TN4592-5mg5mg£504.00
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Quantity:
TAR-TN4592-1mL1 mL * 10 mM (in DMSO)£512.00
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Further Information

Bioactivity:
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100. Murrangatin exhibits antibacterial activity against P. gingivalis (ATCC 33277). Murrangatin also shows soluble epoxide hydrolase inhibitory activity with IC50 values 13.9?6.5uM. Murrangatin and murracarpin may be a new backbone for developing inhibitors of cyclooxygenase 2, they show chondroprotective activity by downregulation of interleukin-1β, tumor necrosis factorα, prostaglandins E2,and matrix metalloproteinases -13, and both of them may be a new backbone for developing inhibitors of cyclooxygenase 2.
CAS:
37126-91-3
Formula:
C15H16O5
Molecular Weight:
276.28
Pathway:
Immunology/Inflammation|GPCR/G Protein|Apoptosis|Neuroscience
Purity:
0.98
SMILES:
COc1ccc2ccc(=O)oc2c1[C@@H](O)[C@@H](O)C(C)=C
Target:
IL Receptor|COX|Prostaglandin Receptor|TNF