TargetMol

NU223612

Product Code:
 
TAR-T74992
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T74992-50mg50mgEnquire
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TAR-T74992-5mg5mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
NU223612 is a potent PROTAC ( PROTACs ) that degrades indoleamine 2,3-dioxygenase 1 (IDO1) ( Indoleamine 2,3-Dioxygenase (IDO) ) with a K d of 640 nM. NU223612 potently degrades the IDO1 protein through CRBN -mediated proteasomal degradation. NU223612 is bound to CRBN with an affinity of 290 nM. NU223612 can cross the blood-brain barrier (BBB) [1] .
CAS:
2759420-43-2
Molecular Weight:
890.99
Purity:
0.98