TargetMol

ONX-0914 TFA

Product Code:
 
TAR-T73986
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T73986-50mg50mgEnquire
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TAR-T73986-5mg5mgEnquire
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ONX-0914 (PR-957) TFA is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7) , the chymotrypsin-like subunit of the immunoproteasome. ONX-0914 TFA blocks cytokine production and attenuates progression of experimental arthritis. ONX-0914 TFA is a noncompetitive irreversible inhibitor of the mycobacterial proteasome (K i =5.2 uM). ONX-0914 TFA reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1 [1] [2] [3] .
Molecular Weight:
694.7
Purity:
0.98