TargetMol

JNK3 inhibitor-4

Product Code:
 
TAR-T72715
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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CodeSizePrice
TAR-T72715-5mg5mg£850.00
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Quantity:
TAR-T72715-50mg50mg£1,661.00
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Quantity:
TAR-T72715-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
JNK3 inhibitor-4 is a potent inhibitor of JNK3 ( IC 50 =1.0 nM) based on 2-aryl-1-pyrimidinyl-1H-imidazole-5-yl acetonitrile. JNK3 inhibitor-4 shows excellent selectivity over other protein kinases including isoforms JNK1 ( IC 50 =143.9 nM) and JNK2 ( IC 50 =298.2 nM) . JNK3 inhibitor-4 has neuroprotective effect and predicated blood-brain barrier permeability .
CAS:
2409109-65-3
Molecular Weight:
477.56
Purity:
0.98
SMILES:
C(C#N)C=1N(C(=NC1)C2=CC3=C(C=C2)C=CC=C3)C4=NC(N[C@@H]5CN(C(=O)C6CC6)CCC5)=NC=C4