TargetMol

EBI-907

Product Code:
 
TAR-T70424
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T70424-5mg5mg£1,251.00
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Quantity:
TAR-T70424-50mg50mg£2,464.00
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Quantity:
TAR-T70424-100mg100mg£3,283.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
EBI-907 is a highly potent and orally efficacious B-RafV600E inhibitor. EBI-907 displays a low single-digit nanomolar activity (IC50 = 4.9 nM), which is >10-fold more potent than Vemurafenib (IC50 = 59 nM). EBI-907 also exhibits high potency in selectively inhibiting the proliferation of BRAF (V600E)-dependent cell lines (A375 and Colo205) and cellular Erk phosporylation, with superior activity to Vemurafenib. EBI-907, displaying potent activity against a number of important oncogenic kinases including BRK, FGFR1, c-Kit, and PDGFRb.
CAS:
1581764-31-9
Molecular Weight:
506.95
Purity:
0.98