TargetMol

AZ0108

Product Code:
 
TAR-T70138
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T70138-5mg5mg£1,733.00
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TAR-T70138-50mg50mg£3,428.00
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Quantity:
TAR-T70138-100mg100mg£4,729.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AZ0108 is an orally bioavailable, potent PARP1,2,6 inhibitor that potently inhibits centrosome clustering and is suitable for in vivo efficacy and tolerability studies. AZ0108 has been utilized as in vitro tools and in vivo probes to investigate the biological consequences of inhibiting centrosome clustering through PARP enzymes. AZ0108 is more selective in its enzyme inhibition profile and effects on cellular pathways and phenotypes. Specifically, AZ0108 inhibits PARPs 1, 2, and 6 with approximately 100-fold selectivity against PARP3 and TNKS1. Consistent with this lack of potencytowards tankyrase, AZ0108 is not active in a DLD-1 Wnt luciferase reporter assay.
CAS:
1825345-52-5
Molecular Weight:
500.4576
Purity:
0.98