TargetMol

BMS-986318

Product Code:
 
TAR-T69686
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T69686-5mg5mg£1,171.00
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Quantity:
TAR-T69686-50mg50mg£2,303.00
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Quantity:
TAR-T69686-100mg100mg£3,042.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BMS-986318 is a potent nonbile acid FXR agonist with EC 50 s of 53 and 350 nM in the FXR Gal4 and SRC-1 recruitment assays, respectively. BMS-986318 has a suitable ADME profile, and demonstrates efficacy in the mouse bile duct ligation model of liver cholestasis and fibrosis.BMS-986318 can be used for the research of nonalcoholic steatohepatitis .
CAS:
2314378-09-9
Molecular Weight:
615.43
Purity:
0.98
SMILES:
O=C(O)C=1N=C2C=CC(=CC2=C(C1)C(F)(F)F)N3CCC4(C=C(C=5C(=NOC5C6CC6)C=7C(Cl)=CN=CC7Cl)C4)CC3