TargetMol

AGPS-IN-2i

Product Code:
 
TAR-T69685
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T69685-5mg5mg£229.00
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Quantity:
TAR-T69685-10mg10mg£336.00
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TAR-T69685-1mL1 mL * 10 mM (in DMSO)£436.00
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TAR-T69685-25mg25mg£522.00
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TAR-T69685-50mg50mg£751.00
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Quantity:
TAR-T69685-100mg100mg£1,099.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells. AGPS-IN-2i had an inhibitory effect on cancer cell proliferation.
CAS:
2316782-88-2
Molecular Weight:
345.34
Pathway:
Proteases/Proteasome
Purity:
0.98
SMILES:
O=C1NC2=CC=C(C=C2N1)CNC(=O)CC(C=3C(F)=CC=CC3F)C
Target:
MMP

References

Stazi G, et al. Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells. Eur J Med Chem. 2019 ; 163:722-735.