TargetMol

JS25

Product Code:
 
TAR-T69646
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T69646-5mg5mg£930.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T69646-50mg50mg£1,821.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T69646-100mg100mg£2,319.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
JS25 is a selective and covalent inhibitor of BTK that inactivates BTK with an IC 50 value of 5.8 nM by chelating Tyr551. JS25 inhibits cancer cells proliferation, pronounces cell death, and promotes murine xenograft model of Burkitt?s lymphoma. JS25 effectively crosses the blood-brain barrier .
CAS:
2411771-95-2
Formula:
C29H24N4O4S
Molecular Weight:
524.59
Purity:
0.98
SMILES:
O=C(C=C)NC=1C=C(C=C(C1)C)N2C(=O)C=CC=3C=NC=4C=C(C=CC4C32)C=5C=CC(=CC5)NS(=O)(=O)C