TargetMol

Endoxifen hydrochloride

Product Code:
 
TAR-T6827L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

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CodeSizePrice
TAR-T6827L-5mg5mg£103.00
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Quantity:
TAR-T6827L-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T6827L-10mg10mg£124.00
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TAR-T6827L-25mg25mg£177.00
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TAR-T6827L-50mg50mg£257.00
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Quantity:
TAR-T6827L-100mg100mg£371.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Endoxifen hydrochloride is a key active metabolite of Tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen hydrochloride has the potential for breast cancer study .
CAS:
1197194-41-4
Molecular Weight:
409.95
Purity:
0.9908
SMILES:
Cl.OC1=CC=C(C=C1)C(C2=CC=C(OCCNC)C=C2)=C(C=3C=CC=CC3)CC

References

Gingery A, et al. The effects of a novel hormonal breast cancer therapy, endoxifen, on the mouse skeleton. PLoS One. 2014;9(5):e98219. Wu X, et al. The tamoxifen metabolite, endoxifen, is a potent antiestrogen that targets estrogen receptor alpha for degradation in breast cancer cells. Cancer Res. 2009;69(5):1722-1727. Goetz MP. Tamoxifen, endoxifen, and CYP2D6: the rules for evaluating a predictive factor. Oncology (Williston Park). 2009;23(14):1233-1236.