TargetMol

Afatinib oxalate

Product Code:
 
TAR-T64075
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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CodeSizePrice
TAR-T64075-5mg5mg£1,167.00
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Quantity:
TAR-T64075-50mg50mg£2,307.00
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Quantity:
TAR-T64075-100mg100mg£2,898.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Afatinib (BIBW 2992) oxalate is an irreversible, orally active bispecific inhibitor of the ErbB family (EGFR and HER2) that acts on EGFRwt (IC50: 0.5 nM), EGFRL858R (IC50: 0.4 nM), EGFRL858R/T790M ( IC50: 10 nM) and HER2 (IC50: 14 nM). Afatinib oxalate can be used to study esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer.
CAS:
1398312-64-5
Molecular Weight:
666.01
Purity:
0.98
SMILES:
OC(=O)C(O)=O.OC(=O)C(O)=O.CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1