TargetMol

Dyrk1A-IN-5

Product Code:
 
TAR-T61739
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T61739-5mg5mg£284.00
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Quantity:
TAR-T61739-50mg50mg£1,187.00
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Quantity:
TAR-T61739-100mg100mg£1,830.00
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This product comes from: United States.
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Further Information

Bioactivity:
Dyrk1A-IN-5 (compound 5j) is a highly potent and selective inhibitor of DYRK1A, exhibiting an IC50 of 6 nM. It dose-dependently diminishes the phosphorylation of Thr434 in SF3B1, with an IC50 of 0.5 uM. Moreover, Dyrk1A-IN-5 effectively inhibits the phosphorylation of tau at Thr212, with an IC50 of 2.1 uM. Given these properties, Dyrk1A-IN-5 is a valuable tool for Down syndrome research [1].
CAS:
1685235-41-9
Molecular Weight:
388.164
Purity:
0.98
SMILES:
OC(=O)c1nc2ccccc2c2[nH]c3c(I)cccc3c12