TargetMol

NMDAR/HDAC-IN-1

Product Code:
 
TAR-T61451
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T61451-5mg5mg£850.00
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Quantity:
TAR-T61451-50mg50mg£1,661.00
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Quantity:
TAR-T61451-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
NMDAR/HDAC-IN-1 (Compound 9d) is a potent dual inhibitor of N-methyl-D-aspartate receptors (NMDARs) and histone deacetylases (HDACs). It exhibits a high affinity (Ki = 0.59 uM) for NMDARs, while demonstrating significant inhibitory effects on various HDAC isoforms, including HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8 with IC 50 values of 2.67 uM, 8.00 uM, 2.21 uM, 0.18 uM, and 0.62 uM, respectively. Moreover, NMDAR/HDAC-IN-1 efficiently crosses the blood-brain barrier [1].
Formula:
C22H28N2O3
Molecular Weight:
368.47
Purity:
0.98