TargetMol

ARN1468

Product Code:
 
TAR-T61256
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T61256-5mg5mg£244.00
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Quantity:
TAR-T61256-50mg50mg£870.00
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Quantity:
TAR-T61256-100mg100mg£1,468.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ARN1468 (compound 5) is a highly effective orally active inhibitor of serpins. Inhibition of serpins activity by ARN1468 enables release of proteases, thereby reducing prion accumulation. ARN1468 demonstrates pronounced anti-prion effects in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC 50 values of 8.64, 19.3, 11.2, and 6.27 uM [1].
CAS:
1381459-14-8
Molecular Weight:
354.333
Purity:
0.98
SMILES:
Nc1c(cnn1-c1ccc(OC(F)(F)F)cc1)C(=O)C1CCNCC1