TargetMol

HPGDS inhibitor 3

Product Code:
 
TAR-T61250
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T61250-5mg5mg£1,167.00
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Quantity:
TAR-T61250-50mg50mg£2,307.00
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Quantity:
TAR-T61250-100mg100mg£2,898.00
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This product comes from: United States.
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Further Information

Bioactivity:
HPGDS inhibitor 3 is a powerful oral compound that selectively inhibits the hematopoietic prostaglandin D synthase (H-PGDS). With an IC50 value of 9.4 nM and EC50 of 42 nM, it demonstrates high potency in peripherally restricting H-PGDS. Moreover, HPGDS inhibitor 3 exhibits excellent selectivity with no associated central nervous system toxicity. This compound also possesses favorable pharmacokinetic properties in mouse, rat, and dog models. Additionally, HPGDS inhibitor 3 displays noteworthy anti-inflammatory activity [1].
CAS:
2255311-93-2
Formula:
C21H27N3O2
Molecular Weight:
353.466
Purity:
0.98
SMILES:
CC(C)(O)[C@H]1CC[C@@H](CC1)NC(=O)c1cnc2nc(ccc2c1)C1CC1