TargetMol

RUNX1/ETO tetramerization-IN-1

Product Code:
 
TAR-T61098
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T61098-5mg5mg£850.00
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Quantity:
TAR-T61098-50mg50mg£1,661.00
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Quantity:
TAR-T61098-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
RUNX1/ETO tetramerization-IN-1 is a small-molecule inhibitor that specifically targets NHR2 of RUNX1/ETO, effectively inhibiting the tetramerization process. With an EC50 value of 0.25 uM, this compound successfully restores gene expression that has been down-regulated by RUNX1/ETO. Furthermore, RUNX1/ETO tetramerization-IN-1 demonstrates promising anti-leukemic activity by inhibiting the proliferation of SKNO-1 cells dependent on RUNX1/ETO and significantly reducing RUNX1/ETO-associated tumor growth in a mouse model [1] [2] [3].
CAS:
88755-39-9
Formula:
C18H14O7
Molecular Weight:
342.303
Purity:
0.98
SMILES:
OC(=O)C(CC(=O)c1ccc2OCOc2c1)c1ccc2OCOc2c1