TargetMol

MS-PPOH

Product Code:
 
TAR-T41291
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T41291-5mg5mg£136.00
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Quantity:
TAR-T41291-10mg10mg£187.00
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Quantity:
TAR-T41291-25mg25mg£283.00
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Quantity:
TAR-T41291-50mg50mg£389.00
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Quantity:
TAR-T41291-100mg100mg£549.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
MS-PPOH is a potent and selective inhibitor of cytochrome P450 (CYP) epoxygenase. MS-PPOH inhibits CYP2C8 and CYP2C9 with IC50s of 15 and 11 uM, respectively
CAS:
206052-02-0
Formula:
C16H21NO4S
Molecular Weight:
323.41
Pathway:
Metabolism
Purity:
0.9842
SMILES:
O=C(NS(=O)(=O)C)CCCCCC=1C=CC=CC1OCC#C
Target:
P450

References

Jun Yang, et al. Cytochrome P450 2C24: Expression, Tissue Distribution, High-Throughput Assay, and Pharmacological Inhibition. Acta Pharm Sin B. 2012 Apr;2(2):137-145. Jing Li, et al. Pharmacological manipulation of arachidonic acid-epoxygenase results in divergent effects on renal damage. Front Pharmacol. 2014 Aug 15;5:187. Kasem Nithipatikom, et al. Inhibition of carcinoma cell motility by epoxyeicosatrienoic acid (EET) antagonists. Cancer Sci. 2010 Dec;101(12):2629-36.