TargetMol

CHMFL-ABL-053

Product Code:
 
TAR-T22067
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T22067-5mg5mg£850.00
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Quantity:
TAR-T22067-50mg50mg£1,661.00
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Quantity:
TAR-T22067-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
CHMFL-ABL-053 (Compound 18a) is a potent, selective, and orally available BCR-ABL, SRC and p38 kinase inhibitor with IC 50 values of 70, 90 and 62 nM against ABL1, SRC and p38, respectively. CHMFL-ABL-053 is a potentially useful drug candidate for Chronic Myeloid Leukemia(CML)[1].
CAS:
1808287-83-3
Molecular Weight:
549.558
Purity:
0.98
SMILES:
CNc1nc(Nc2ccc(C)c(N)c2)ncc1C(=O)Nc1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C