TargetMol

cRIPGBM

Product Code:
 
TAR-T19250
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T19250-5mg5mg£1,167.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T19250-50mg50mg£2,307.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T19250-100mg100mg£2,898.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
cRIPGBM is a proapoptotic derivative of RIPGBM. cRIPGBM is a cell type-selective inducer of apoptosis in GBM cancer stem cells (CSCs) by binding to receptor-interacting protein kinase 2 (RIPK2), with an EC 50 of 68 nM in GBM-1 cells [1].
CAS:
2361988-76-1
Molecular Weight:
411.45
Pathway:
Apoptosis
Purity:
0.98
SMILES:
O=C1C2=C([N+](CC3=CC=CC=C3)=C(C)N2CC4=CC=CC=C4)C(C5=C1C=CC=C5)=O
Target:
TNF

References

Lucki NC, et al. A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6435-6440.