TargetMol

Cortistatin-14 acetate

Product Code:
 
TAR-TP1570L
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

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CodeSizePrice
TAR-TP1570L-1mg1mg£161.00
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Quantity:
TAR-TP1570L-5mg5mg£422.00
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TAR-TP1570L-10mg10mg£500.00
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TAR-TP1570L-25mg25mg£701.00
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TAR-TP1570L-50mg50mg£1,010.00
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Quantity:
TAR-TP1570L-100mg100mg£1,340.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Cortistatin-14 acetate, a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 acetate shows anticonvulsive, neuroprotective effect and remarkable anti-inflammatory properties
Molecular Weight:
1780.08
Pathway:
GPCR/G Protein
Purity:
0.9824
SMILES:
O=C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@](NC([C@@H](NC1=O)CCCCN)=O)([H])[C@H](O)C)=O)CC2=CC=CC=C2)=O)CO)=O)CO)=O)C(N[C@H](C(N)=O)CCCCN)=O)NC([C@@H]3CCCN3)=O)=O)CCCCN)=O)CC(N)=O)=O)CC4=CC=CC=C4)=O)CC5=CC=CC=C5)N[C@H]1CC6=CNC7=CC=CC=C67.CC(O)=O
Target:
Somatostatin

References

Baranowska B, et al. Cortistatin and pituitary hormone secretion in rat. J Physiol Pharmacol. 2009 Mar;60(1):151-6. Braun H, et al. Protective effects of cortistatin (CST-14) against kainate-induced neurotoxicity in rat brain. Brain Res. 1998 Aug 24;803(1-2):54-60. De Lecea L, et al. A cortical neuropeptide with neuronal depressant and sleep-modulating properties. Nature. 1996 May 16;381(6579):242-5. Markovics A, et al. Comparison of the anti-inflammatory and anti-nociceptive effects of cortistatin-14 and somatostatin-14 in distinct in vitro and in vivo model systems. J Mol Neurosci. 2012 Jan;46(1):40-50.