TargetMol

BIRM 271

Product Code:
 
TAR-T77638
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T77638-1mg1mg£227.00
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TAR-T77638-5mg5mg£416.00
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TAR-T77638-10mg10mg£581.00
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TAR-T77638-25mg25mg£863.00
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TAR-T77638-50mg50mg£1,163.00
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TAR-T77638-100mg100mg£1,540.00
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Quantity:
TAR-T77638-500mg500mg£3,026.00
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Further Information

Bioactivity:
BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. BIRM 271 and BIRM 270 are enantiomers that inhibit the production of leukotriene B4 with IC50 of 40 nM.
CAS:
149106-77-4
Molecular Weight:
335.44
Pathway:
Immunology/Inflammation|Metabolism
Purity:
0.9938
SMILES:
N([C@H](CC1CCCCC1)C2=CC=CC=N2)C=3OC=4C(N3)=CC(C)=CC4
Target:
LTR|Phospholipase

References

Farina PR, et al. BIRM 270: a novel inhibitor of arachidonate release that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. J Pharmacol Exp Ther. 1994;271(3):1418-1426.