TargetMol

Enpp/Carbonic?anhydrase-IN-2

Product Code:
 
TAR-T77631
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

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CodeSizePrice
TAR-T77631-1mg1mg£145.00
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TAR-T77631-5mg5mg£255.00
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TAR-T77631-1mL1 mL * 10 mM (in DMSO)£267.00
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TAR-T77631-10mg10mg£369.00
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TAR-T77631-25mg25mg£573.00
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TAR-T77631-50mg50mg£787.00
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Quantity:
TAR-T77631-100mg100mg£1,050.00
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Quantity:
TAR-T77631-500mg500mg£2,022.00
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This product comes from: United States.
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Further Information

Bioactivity:
Enpp/Carbonic?anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.07, 0.74, 0.33, 0.68, respectively.Enpp/Carbonic?anhydrase-IN-2 induced apoptosis.Enpp/Carbonic anhydrase-IN-2 has antiproliferative activity against cancer cells and low cytotoxicity against normal cells.
CAS:
2883495-39-2
Molecular Weight:
429.5
Pathway:
Apoptosis|Metabolism
Purity:
0.98
SMILES:
O=C(NC1=CC=C(OS(=O)(=O)C2=CC=C(F)C=C2)C=C1)C34CC5CC(CC(C5)C3)C4
Target:
Carbonic Anhydrase|PDE|Apoptosis

References

Shahin AI, et al. Design and synthesis of new adamantyl derivatives as promising antiproliferative agents. Eur J Med Chem. 2023 Jan 15;246:114958.