TargetMol

Z16078526

Product Code:
 
TAR-T77621
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T77621-1mg1mg£109.00
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TAR-T77621-5mg5mg£165.00
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TAR-T77621-10mg10mg£227.00
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TAR-T77621-25mg25mg£404.00
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TAR-T77621-50mg50mg£566.00
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TAR-T77621-100mg100mg£775.00
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Quantity:
TAR-T77621-500mg500mg£1,508.00
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Quantity:
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Further Information

Bioactivity:
Z16078526 induces endogenous Ucp1 expression, promotes?p38 MAPK?phosphorylation and lipolysis in primary mouse brown adipocytes. Z16078526 activates thermogenic gene expression and mitochondrial activity (uncoupled respiration) in mouse brown adipocytes. Z16078526 also stimulates thermogenesis in the mouse
CAS:
852222-94-7
Formula:
C18H17N3O4S
Molecular Weight:
371.41
Pathway:
Metabolism|MAPK
Purity:
0.98
SMILES:
O=C1N=C(SCC(=O)NC2=CC=C(OC)C=C2OC)NC=3C=CC=CC13
Target:
p38 MAPK|Mitochondrial Metabolism

References

Vergnes L, et al. Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation. J Biol Chem. 2020 Oct 30;295(44):15054-15069.