TargetMol

5-LOX-IN-2

Product Code:
 
TAR-T77528
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T77528-1mg1mg£112.00
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Quantity:
TAR-T77528-5mg5mg£226.00
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Quantity:
TAR-T77528-10mg10mg£338.00
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TAR-T77528-25mg25mg£550.00
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Quantity:
TAR-T77528-50mg50mg£768.00
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Quantity:
TAR-T77528-100mg100mg£1,018.00
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Quantity:
TAR-T77528-500mg500mg£1,990.00
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Quantity:
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Further Information

Bioactivity:
5-LOx-in-2 is a 5-lipoxygenase inhibitor (5-LOX) with an IC50 value of 0.33 uM. 5-lox-in-2 inhibits 5-LOX action IN a dose-dependent manner. 5-LOX-IN-2 can reduce the cell activity of kidney cancer cells and induce apoptosis, and can be used in cancer research.
CAS:
179691-97-5
Formula:
C17H16O4
Molecular Weight:
284.31
Pathway:
Apoptosis|Metabolism
Purity:
0.98
SMILES:
C(=C/C(OCCC1=CC=CC=C1)=O)\C2=C(O)C=CC(O)=C2
Target:
Lipoxygenase|Apoptosis

References

Selka A, et.al. Discovery of a novel 2,5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells. Eur J Med Chem. 2019 Oct 1;179:347-357.