TargetMol

Aloisine B

Product Code:
 
TAR-T69188
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T69188-1mg1mg£352.00
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Quantity:
TAR-T69188-5mg5mg£736.00
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TAR-T69188-10mg10mg£978.00
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TAR-T69188-25mg25mg£1,348.00
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Quantity:
TAR-T69188-50mg50mg£1,661.00
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Quantity:
TAR-T69188-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Aloisine B inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 uM and 0.75 uM, respectively. Aloisine B has antiviral activity and can be used to study Alzheimer's, diabetes, HIV and Parkinson's.
CAS:
496864-14-3
Molecular Weight:
271.74
Pathway:
Cell Cycle/Checkpoint|Stem Cells|PI3K/Akt/mTOR signaling
Purity:
0.9515
SMILES:
ClC1=CC=C(C=C1)C=2NC=3N=CC=NC3C2C(C)C
Target:
GSK-3|CDK

References

Mettey Y, et al. Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects. J Med Chem. 2003 Jan 16;46(2):222-36.