TargetMol

Trifluoromethyl-tubercidin

Product Code:
 
TAR-T67753
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T67753-1mg1mg£335.00
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TAR-T67753-5mg5mg£711.00
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TAR-T67753-1mL1 mL * 10 mM (in DMSO)£792.00
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TAR-T67753-10mg10mg£946.00
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TAR-T67753-25mg25mg£1,396.00
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TAR-T67753-50mg50mg£1,862.00
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Quantity:
TAR-T67753-100mg100mg£2,424.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Trifluoromethyl-tubercidin (TFMT) inhibits host MTr1 and suppresses virus replication. TFMT inhibits MTr1 through interaction at its S-adenosyl-l-methionine binding pocket to restrict influenza virus replication. TFMT was effective in inhibiting viral replication in mice, displayed little toxicity.
CAS:
1854086-05-7
Molecular Weight:
334.25
Pathway:
Microbiology/Virology
Purity:
1
SMILES:
O[C@H]1[C@H](N2C=3C(C(C(F)(F)F)=C2)=C(N)N=CN3)O[C@H](CO)[C@H]1O
Target:
Influenza Virus

References

Tsukamoto Y, et al. Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science. 2023 Feb 10;379(6632):586-591.