TargetMol

SLP9101555

Product Code:
 
TAR-T63047
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T63047-1mg1mg£352.00
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Quantity:
TAR-T63047-1mL1 mL * 10 mM (in DMSO)£631.00
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Quantity:
TAR-T63047-5mg5mg£736.00
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Quantity:
TAR-T63047-10mg10mg£978.00
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Quantity:
TAR-T63047-25mg25mg£1,348.00
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Quantity:
TAR-T63047-50mg50mg£1,661.00
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Quantity:
TAR-T63047-100mg100mg£2,079.00
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Quantity:
TAR-T63047-500mg500mg£4,006.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
SLP9101555 is a potent and selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of 90 nM.SLP9101555 has a high affinity for SphK2, which is 200-fold higher than that of SphK1.SLP9101555 dramatically reduces extracellular S1P sphingosine 1-phosphate (S1P) levels.
CAS:
T63047
Molecular Weight:
357.72
Pathway:
GPCR/G Protein
Purity:
0.994
SMILES:
Cl.BrC=1C=CC2=C(C1)NC(=C2CCNC)C(C=C)(C)C
Target:
LPL Receptor|S1P Receptor

References

Pashikanti S, et al. Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues. ACS Bio Med Chem Au. 2022;2(5):469-489.