TargetMol

(S)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide

Product Code:
 
TAR-T60186
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T60186-1mg1mg£227.00
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TAR-T60186-2mg2mg£306.00
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TAR-T60186-5mg5mg£431.00
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TAR-T60186-1mL1 mL * 10 mM (in DMSO)£502.00
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TAR-T60186-10mg10mg£600.00
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TAR-T60186-25mg25mg£863.00
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Quantity:
TAR-T60186-50mg50mg£1,187.00
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Quantity:
TAR-T60186-100mg100mg£1,581.00
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Quantity:
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This product comes from: United States.
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Further Information

CAS:
1934246-20-4
Formula:
C26H23F3N6O
Molecular Weight:
492.5
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9987
SMILES:
C[C@H]1C=2C(CN(C1)C=3C=NC=NC3)=CC(C(NC4=CC(=CC(C(F)(F)F)=C4)N5C=NC(C)=C5)=O)=CC2
Target:
Discoidin Domain Receptor (DDR)

References

Wang Z, Bian H, Bartual SG, Du W, Luo J, Zhao H, Zhang S, Mo C, Zhou Y, Xu Y, Tu Z, Ren X, Lu X, Brekken RA, Yao L, Bullock AN, Su J, Ding K. Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors. J Med Chem. 2016 Jun 23;59(12):5911-6. doi: 10.1021/acs.jmedchem.6b00140. Epub 2016 Jun 3. PMID: 27219676; PMCID: PMC5053573.